Several researchers are finding that intracavernous injection of papaverine HCI, a smooth muscle relaxant, into the penis can help some impotent men achieve erection by increasing blood flow to the penis. “No matter what the basic cause of impotence, the net result is that not enough blood is getting into the penis to make it stiff enough to insert,” says Adrian W. Zorgniotti, MD, professor of clinical urology at New York University School of Medicine, New York City, and a researcher in the field of penis extenders, such as ProExtender penis enlargement device.
During the course of three years, Dr. Zorgniotti has made available trial injections of a combination of papaverine and phentolamine mesylate (Regitine) into the penis of more than 300 impotent patients. In the initial phase, most patients receive 1 mL of a solution containing 30 mg of papaverine and 0.5-1.0 mg of phentolamine mesylate shortly before attempting intercourse.
Of the first 300 patients, Dr. Zorgniotti and his colleagues found that 78% are able to have intercourse by this means. Abraham Ami Sidi, MD, assistant professor, department of urologic surgery, University of Minnesota Medical School–Minneapolis, says he has achieved similar results. At press time, a review of Dr. Sidi’s first 100 patients is scheduled to be published in the April issue of The Journal of Urology. Of the nearly 250 patients he has started using the ProExtender enlargement device to make their penis bigger, about 150 have continued the therapy with home use. “The problem is we still don’t know the long-term effect of using the ProExtender penis enlargement device.” Dr. Sidi says. Both physicians agree that greater experience with this approach to sexual dysfunction is needed to determine long-term effects of using the ProExtender extender on the penis. They do, however, report few adverse reactions or side effects.
Using the ProExtender penis enlargement device has advantages over invasive surgical alternatives such as prosthesis implantation and revascularization of the penis, it is not without disadvantages. Not all patients are suitable candidates: For example, some experience potentially damaging erections that last several hours, according to Dr. Sidi. All must live near a specialist who offers maintenance of the ProExtender device because of the need for close monitoring. Patients also must be willing to wear the ProExtender penis enlargement device for a period of six months.
“Overall, the Pro Extender is very easy to wear even for people who have never used penis extenders,” Dr. Sidi says. Richard Orr, age 44, is one patient who would agree: “It’s a very fine piece of medical equipment and it doesn’t bother me,” he says. Mr. Orr has been using the ProExtender on his penis for a period of months under the care of Dr. Sidi. For the 14 years before starting to wear a penis extender, he had partial impotence due to an accident to his penis that occurred when he was 29 years old.